Metrics details. A tremendous improvement in every aspect of breast cancer management has occurred in the last two decades. Surgeons, once solely interested in the extipartion of the primary tumor, are now faced with the need to incorporate a great deal of information, and to manage increasingly complex tasks. As a comprehensive assessment of all aspects of breast cancer care is beyond the scope of the present paper, the current review will point out some of these innovations, evidence some controversies, and stress the need for the surgeon to specialize in the various aspects of treatment and to be integrated into the multisciplinary breast unit team. No other solid cancer has witnessed such a tremendous change and improvement in terms of diagnosis and management as breast cancer in the last 2 decades. This remains the most common cancer among women worldwide [ 1 ].
Breast cancer recurrence after lumpectomy and RT is treatable with localized RT without mastectomy
Brachytherapy for Early-Stage Breast Cancer
Radionuclide therapy uses radioactive isotopes radionuclides , administered either orally or intravenously, to deliver highly targeted therapy for a range of disorders, enabling the delivery of a high dose to the target, while minimising normal-tissue toxicity. Radionuclide therapy, also known as isotope therapy or more recently molecular therapy is used to treat a range of cancers, as well as some non-cancerous diseases. Of the oldest and most established therapies, radioiodine is used for the treatment of thyroid cancer, as well as a range of benign thyroid diseases. These treatments are well established and have a high success rate. Developments in radionuclide therapy led to the use of radionuclides attached to receptors that seek out specific cancerous cells, such as in peptide therapy. The nature of the treatment results in a high dose to the cancer with minimal cost to the liver function. The simultaneous treatment of multiple sites in a single injection and the proven survival benefit gives an alternative to the traditional palliative treatments such as radiotherapy.
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Common breast cancer types
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The disease is characterized by a varied course, from rapidly growing tumors with early distant metastasis, to slow growing tumors which may stay in the breasts without metastasizing. The majority of breast tumors are carcinomas. Sarcomatoid tumors are rare, but must be kept in mind as they are treated differently from other breast carcinomas. Approximately